Last Updated: 18 September 2022
Figure 1. The denaturation and hydrolisis of Collagen into Hydrolysed Collagen.
Hydrolysed Collagen (HC) is a group of peptides with low molecular weight that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature. HC is obtained via the denaturation of Collagen triple helix and subsequently hydrolysis by proteolytic enzymes (e.g. alcalase, papain, pepsin). Taken as a dietary supplement, HC provides the same benefits as Collagen.
Nevertheless, HC presents several practical advantages compared to Collagen, including having a higher therapeutic loading, cost-effectiveness (not requiring a multistep extraction procedure), highly digestible and is easily absorbed and distributed within the human body. Furthermore, HC exhibits lower viscosity in aqueous solution, neutral in odour, is colourless, is transparent, has a wide range of solubility, and has low allergenicity.
For nutritional values, refer to the Codex entry for Collagen.
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* Please be advised: always seek medical consultation if you require medical help or attention. The contents of this Codex are for educational purposes and are not intended to offer personal medical advice.